Rob Vescovo Republican Dean Plocher Republican The 2022 Missouri House of Representatives election took place on Tuesday, November 8, 2022, with the primary election held on Tuesday, August 2, 2022.

[10] David Tyson Smith (D) won the subsequent special election, holding the seat for his party.

At 52 members, Democrats gained their largest share of House seats since 2012.

[21] These were the first elections in Missouri following the 2020 United States redistricting cycle, which resulted in redrawn legislative district boundaries.

[22][23] Sources for special election results:[9][10][11][12][13] Seats where the margin of victory was under 10%: Italics denote an open seat held by the incumbent party; bold text denotes a gain for a party.