The 2022 Orlando USTA Pro Circuit Event 2 was a professional tennis tournament played on outdoor hard courts.

It was the fourth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour.

It took place in Orlando, Florida, United States between 23 and 29 May 2022.

[1] The following players received wildcards into the singles main draw: The following player received entry using a protected ranking: The following players received entry from the qualifying draw: