The 2022 Rio Grande Valley FC Toros season was the 7th season for Rio Grande Valley FC Toros in USL Championship (USLC), the second-tier professional soccer league in the United States and Canada.

[1] This article covers the period from November 29, 2021, the day after the 2021 USLC Playoff Final, to the conclusion of the 2022 USLC Playoff Final, scheduled to be completed before November 14, 2021.

[2] Note: Flags indicate national team as defined under FIFA eligibility rules.

With the end of their affiliation agreement with the Houston Dynamo, Rio Grande Valley FC is eligible to compete in the U.S. Open Cup for the first time in club history in 2022.

Numbers after plus-sign(+) denote appearances as a substitute.