[1] Expansion clubs On hiatus Departing clubs Joined MLS Next Pro[8] In December 2021, it was announced that divisional play would be dropped and that there would be 2 conferences, Eastern and Western.
They further announced a 34-game schedule, with each team playing their conference opponents twice, with the Eastern Conference filling out the 8 remaining games with interconference opponents.
In the Western Conference, the 10 remaining games would be competed with intraconference and interconference opponents.
[1] Championship Game MVP: Santiago Patiño (SAN)
1 One result missing 2 Two results missing Updated to games of April 16, 2022.Sources: USL Championship & Soccer Stadium Digest