District 1 was an open seat due to the terming out of Supervisor Mike Wasserman.

[1] The race was highly competitive and the first since the 2020 United States redistricting cycle which changed the boundaries of the district.

[2] Since District 4 was uncontested, incumbent Supervisor Susan Ellenberg did not appear on the November 8th ballot.

All local elections in California are officially nonpartisan and use a top-two primary system; if no candidate receives a majority of the June 7, 2022 vote, a runoff was held between the top two candidates on November 8, 2022.

In the redistricting process, the district lines were changed during a contentious process in which one of the candidates, Johnny Khamis, threatened to sue for alleged gerrymandering.