The 2022 St. Petersburg Ladies' Trophy was a professional tennis tournament played on indoor hard courts.

It was the 13th edition of the event and a WTA 500 tournament on the 2022 WTA Tour.

It was held between 6 and 13 February 2022.

[1] 1Qualifiers prize money is also the Round of 32 prize money.

*per team The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry as a lucky loser : The following pair received a wildcard into the doubles main draw: