Cheney's margin of defeat marked the second-worst for a House incumbent in the last 60 years, behind that of South Carolina Republican Bob Inglis in a 2010 primary runoff.

Incumbent Liz Cheney was criticized by supporters of former president Donald Trump for her vote to impeach him, as well as refusing to object to the certification of the Electoral College results in the 2020 presidential election.

Later that year, it also voted 31–29 to no longer recognize Cheney as a member due to her actions to participate in the January 6 Select Committee shortly after being removed as Conference Chair.

[6][7] In February 2021, members of the Freedom Caucus attempted to have Cheney removed from her position as Chair of the House Republican Conference in response to her impeachment vote.

[9] On May 21, 2021, challenger Anthony Bouchard admitted that as a teenager he fell in love with and started dating a 14-year-old girl who he subsequently impregnated and then married.

This prompted Cheney to release the full audio recording of the call which showed that she did, in fact, concede the race.

[72] Aggregate polls Graphical summary In the general election, Hageman faced Democratic nominee and Native American activist Lynnette Grey Bull, who was Cheney's opponent in 2020.

[89] Republicans had a nearly 7-to-1 advantage in registration over Democrats,[90] and Trump carried the state in 2020 with almost 70 percent of the vote, his strongest state-level performance in the nation.

Counties that flipped from Republican to Democratic Partisan clients Official campaign websites for candidates