At an event in 2021, United States Senator Ted Cruz (R-TX), claimed that the "road to the majority...comes through Iowa.

The 1st district was based in northeastern Iowa, and included the cities of Dubuque, Cedar Rapids and Waterloo.

The reconfigured 2nd is located in northeastern Iowa and includes Dubuque, Cedar Rapids, Waterloo and Mason City.

Freshman Republican Ashley Hinson, who flipped the district with 51.2% of the vote in 2020, sought reelection in the 2nd.

Senators U.S. Executive Branch officials Organizations Aggregate polls Graphical summary Generic Democrat vs. generic Republican Randy Feenstra Republican Randy Feenstra Republican Before redistricting, the 4th district was based in northwestern Iowa, including Sioux City, Ames, Mason City, Fort Dodge, Boone and Carroll.