Ahead of the 2022 elections, Oregon redrew its congressional districts as part of the 2020 United States redistricting cycle.

Tina Kotek, the Democratic speaker of the Oregon House of Representatives, had negotiated a deal with Republicans to give them equal say on redistricting matters, but she abandoned the deal after the Senate passed its maps.

[5] On September 27, the legislature's deadline to approve new maps, most House Republicans showed up to vote.

[7] Organizations Labor unions Cliff Bentz Republican Cliff Bentz Republican From 2012 to 2020, the 2nd district was the largest of Oregon's districts and covered roughly two-thirds of the state east of the Cascades, encompassing the central, eastern, and southern regions of the state, including Bend and Medford.

[7] Organizations Labor unions Peter DeFazio Democratic Val Hoyle Democratic From 2012 to 2020, the 4th district included the southern Willamette Valley and the South Coast, including Eugene, Corvallis, and Roseburg.

The incumbent, Democrat Peter DeFazio, who was re-elected with 51.5% of the vote in 2020,[7] decided to retire, rather than seek a 19th consecutive term in Congress.

The new 5th district keeps the southern suburbs of Portland and reaches further into the city, but does not include any coastline, instead stretching southwards through the eastern parts of Marion and Linn counties to Bend.