[2] Jo Rae Perkins, who unsuccessfully ran for Oregon's other Senate seat in 2020, won the Republican primary with 33.3% of the vote.

[3] The four candidates filing with the Oregon Secretary of State for this election included Chris Henry of the Oregon Progressive Party and Dan Pulju of the Pacific Green Party.

This was the first time since 1996 that none of the following counties went Democratic in a Senate Class III election: Gilliam, Jackson, Marion, Polk, Wasco, and Yamhill.

It was also the first time Columbia County supported the Republican nominee in this seat since 1986.

Senators Organizations Labor unions Newspapers Individuals Counties that flipped from Democratic to Republican Wyden won 5 of 6 congressional districts, including one that elected a Republican.