The Blue Devils were led by fourth year head coach Kara Lawson and played their home games at Cameron Indoor Stadium in Durham, North Carolina as members of the Atlantic Coast Conference.

They would win their next two games, including another overtime victory, this time against Georgia in the ACC–SEC Challenge.

Duke would lose its next two games, one against first-ranked South Carolina and the other, its ACC opener at Clemson.

Losses game against twelfth-ranked Virginia Tech and nineteenth-ranked Notre Dame while they defeated seventeenth-ranked Syracuse and sixth-ranked NC State.

They received an at-large bid to the NCAA Tournament and were the third seed in the Seattle 4 Region.