3-Aminopyridine

It is a colorless solid.

[1] 3-Aminopyridine is prepared by heating nicotinamide with sodium hypobromite (Hofmann rearrangement), which is in turn prepared in situ by the reaction of sodium hydroxide and bromine at 70 °C.

[2] It can be used in the synthesis of organic ligand 3-pyridylnicotinamide.

Troxipide is another synthesis that uses 3-AP.

The acute toxicity is indicated by the LD50 = 178 mg/kg (quail, oral).