Therefore, adaptor proteins are responsible for the recruitment of cargo molecules into a growing clathrin-coated pits.
[3][4] Adaptins are distantly related to the other main type of vesicular transport proteins, the coatomer subunits, sharing between 16% and 26% of their amino acid sequence.
[5] Adaptor protein (AP) complexes are found in coated vesicles and clathrin-coated pits.
Mu recognises tyrosine-based sorting signals within the cytoplasmic domains of transmembrane cargo proteins.
[9] One function of clathrin and AP2 complex-mediated endocytosis is to regulate the number of GABAA receptors available at the cell surface .