[1] Khare made her acting debut in 2014 through producer director Lal Vijay Shahdeo's drama series Yeh Shaadi Hai Ya Sauda on DD National.
In 2016, Khare played the parallel lead in drama series Jaane Kya Hoga Rama Re which aired on Life OK.
In 2016, she played the role of Aparajita in Zee TV’s supernatural drama series Vishkanya Ek Anokhi Prem Kahani.
Later on, she played the lead in political drama Saam Daam Dand Bhed as Bulbul Namdhari, Vijay's wife and love interest.
[citation needed] In 2019, she was roped in by Ekta Kapoor for cameo in her drama series Yeh Hai Chahatein on StarPlus where she played the role of Mahima Srinivasan, sister of the protagonist, later on her role turned into an antagonist.