In Jean Scherrer's laboratory, he turned to neurophysiology and initiated research work on inhibitory synapses with Henri Korn, a specialist in the field.
Since 2011, he has also been Director of the MemoLife Laboratory of Excellence,[1] whose biology, physics and mathematics teams address memory processes, from genes to neural networks and the mechanisms of evolution.
He created his laboratory at the École normale supérieure de la rue d'Ulm in 1995 and reoriented his activities towards the study of the molecular and cellular mechanisms that control the recruitment and trafficking of receptors in the synapse.
This technological advance makes it possible to move from static imaging of molecules to a very high resolution dynamic approach.
[1] It is the subject of a founding article in Science[8] that highlights multiple molecular mechanisms responsible for regulating these movements and ultimately the intensity of information transmission between neurons.
[9][10][11][12] Triller has contributed to a new understanding of the mechanisms of addressing stability and plasticity of the synapse, making it possible to broaden pharmacological approaches to neural dysfunctions.