Applied Maths was founded in 1992 and gained worldwide recognition with the software GelCompar, used as a standard tool for the normalization and comparative analysis of electrophoresis patterns (PFGE, AFLP, RAPD, REP-PCR and variants, etc.).

[1][2] GelCompar II was released in 1998 to deal with the ever growing amounts of information following the success and expansion of electrophoresis and other fingerprinting techniques in various application fields in microbiology, virology and mycology.

Following the introduction of the concepts of polyphasic taxonomy [3] and the growing need to combine genotypic, phenotypic, electrophoresis and sequence information, Applied Maths released in 1996 the software package BIONUMERICS which still today is a platform for the management, storage and (statistical) analysis of all types of biological data.

[4] BIONUMERICS and GelCompar II are used by several networks around the globe, such as PulseNet and CaliciNet, to share and identify strain information.

Over 20,000 peer-reviewed research articles mention the use of Applied Maths software packages BIONUMERICS or Gelcompar II.