The highway itself is split into two sections, both of which are mainly located in southwest Arkansas.

The first section begins at U.S. Route 70 (US 70) just east of Welsh, and ends at AR 84 in Amity.

The route travels almost directly south for about 7.2 miles (11.6 km) until it reaches its eastern terminus at AR 84 in Amity.

The route itself does not intersect any other communities or highways, but it does cross the Caddo River shortly before its eastern terminus.

The route heads towards the southeast for about 12.4 miles (20.0 km) before reaching its eastern terminus at the concurrency of US 67 and AR 53 in Gurdon.