The route of 17.77 miles (28.60 km) runs from Highway 306 near Caldwell north across US Route 64 (US 64) through rural Cross County to Highway 42 near Hickory Ridge.

[2][3] The route has an officially designated exception of 0.49 miles (0.79 km) over Highway 284.

[4] AR 193 begins near Caldwell at Highway 306 in northwest St. Francis County.

[2] The route continues north to an officially designated exception of 0.49 miles (0.79 km) with Highway 284.

The route overlaps with US 64 east for 0.9 miles (1.4 km), after which Highway 193 turns north.