Arogenate dehydratase

Other names in common use include: The carboxyl and hydroxide groups (shown in red) attached to the 2,5-cyclohexene ring are eliminated from L-arogenate, leaving as carbon dioxide and water.

The carboxyl and hydroxide groups (in red) attached to the 2,5-cyclohexene ring are removed, leaving phenylpyruvate.

ADT catalyzes a reaction categorized by two major changes in the structure of the substrate, these being a decarboxylation and a dehydration; the enzyme removes a carboxyl group and a water molecule (respectively).

[5] Homologues for ADT have been isolated in Arabidopsis thaliana (rabbit-ear cress),[5] Nicotiana sylvestris (tobacco),[6] Spinacia oleracea (spinach),[6] Petunia hybrida,[7] Sorghum bicolor,[8] Oryza sativa,[9] and Pinus pinaster[10] which are all considered higher-order plants.

Of the plants with ADT homologues, both Arabidopsis thaliana, Petunia hybrida, and Pinus pinaster are known to have paralogues for the gene (six, three, and nine, respectively).

Arogenate dehydratase converting L-arogenate to L-phenylalanine, carbon dioxide, and water
Arogenate dehydratase converting prephenate to phenylpyruvate, carbon dioxide and water