BMPR1A

[5] BMP's repress WNT signaling to maintain stable stem cell populations.

BMPR1A null mice died at embryonic day 8.0 without mesoderm specification, demonstrating its vital role in gastrulation.

[6] It has been demonstrated in experiments using dominant negative BMPR1A chick embryos that BMPR1A plays a role in apoptosis and adipocyte development.

[6] Using constitutively active forms of BMPR1A, it has been shown that BMPR1A plays a role in cell differentiation.

[6] In the chick embryo, BMPR1A receptors are found in low levels in limb bud mesenchyme, a differing location to BMPR1B, supporting the differing roles they play in osteogenesis.