The Bayshore Route is a 62.1-kilometer (38.6 mi) stretch of toll highway that runs from the Kanazawa ward of Yokohama in the west, northeast to the city of Ichikawa in Chiba Prefecture in the east.

The Bayshore Route runs from Yokohama across the Yokohama Bay and Tsurumi Tsubasa Bridges, through the Kawasaki Subsea, the Tama Subriver, Haneda Airport North, and Tokyo Bay Subsea Tunnels, which connects it to the popular tourist spot of Odaiba, and then on to Urayasu (near Tokyo Disneyland) in Chiba Prefecture.

The expressway facilitates direct road travel between Chiba and Kanagawa prefectures as well as Narita and Haneda Airports.

[5] The Ministry of Land, Infrastructure, Transport and Tourism (MLIT), conducts surveys on the Japan's national routes and expressways every five years to measure their average daily traffic.

In 2015, the most utilized point along the expressway was in the Kōtō ward of Tokyo between Tatsumi Junction and Shinkiba, where a daily average of 163,404 vehicles traveled on the Bayshore Route.

The least busy section of the expressway was in Yokohama between its western terminus and the interchange at Sugita, there it carried an average of only 27,268 vehicles.

[10] The final stage of the project was completed in March 2008 with the widening of the eastbound section of the Bayshore Route between Tatsumi and Ariake Junction.

[12] On 4 March 2017, the interchange at Minami-honmoku futō in Yokohama was completed, providing a direct connection from the Bayshore Route to Honmoku Wharf by a 2.5-kilometer-long (1.6 mi) viaduct.