It strives to provide a comprehensive curated resource for all major model organism species while attempting to remove redundancy to create a single mapping of data.

[16] BioGRID data are freely distributed through partner model organism databases and meta-databases and are directly downloadable in a variety of formats.

As of 18 October 2020[update],[15] BioGRID themed curation project efforts have resulted in the extraction of 424,631 interactions involving 2,361 proteins from more than 37,000 scientific articles.

CRISPR-based genetic screens have now been reported in numerous publications that link gene function to cell viability, chemical and stress resistance, and other phenotypes.

As of 18 October 2020[update],[15] BioGRID-ORCS contains more than 1,042 CRISPR screens curated from 114 publications representing more than 60,000 unique genes across three species human (Homo sapiens), fruit fly (Drosophila melanogaster), and house mouse (Mus musculus) in over 670 cell lines and 17 phenotypes.