Blaine is a home rule-class city in Lawrence County, Kentucky, United States.

Blaine was originally settled c. 1800 and established as a local trade center by 1882.

Although the city was incorporated as "Blaine" on March 10, 1886, it was alternatively known as "Blainetown" or "Mouth of Hood" for the remainder of the 19th century.

According to the United States Census Bureau, the city has a total area of 0.29 square miles (0.74 km2), of which 0.43 acres (1,757 m2), or 0.24%, are water.

About 29.4% of families and 39.0% of the population were below the poverty line, including 51.8% of those under the age of eighteen and 21.2% of those 65 or over.

[11] The climate in this area is characterized by relatively high temperatures and evenly distributed precipitation throughout the year.