In the 2007–08 season, Sănătatea narrowly avoided relegation, finishing 14th in Series VI but also achieved one of the greatest performances in club history by reaching the Round of 16 in Cupa României.

The fourth round brought a stunning 1–0 victory over Gaz Metan Mediaș, followed by wins against Unirea Alba Iulia (3–2) and top-flight side UTA Arad (1–0).

In the following season, the "Green Viruses" reached the Round of 32 in Cupa României after eliminating higher-ranked teams such as Universitatea Cluj and FCM Târgu Mureș, both with 1–0 victories.

The squad for that match consisted of S. Pâglișan, C. Miclăuș, C. Sărmășan, S. Sos, C. Kiss, A. Albu, A. Simioancă, A. Gașpar ('81 A. Ghișa), S. Crișan, R. Rus ('69 R. Hoca), and I. Ganea ('46 C. Nicula).

Liga IV – Cluj County Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.