Calcium carbimide, sold as the citrate salt under the trade name Temposil, is a disulfiram-like medication.

The result is that when alcohol is consumed by users of calcium carbimide, they experience severe reactions which include symptoms such as sweating, difficulty breathing, rapid heartbeat, rash, nausea and vomiting, and headache.

A recent 9-year study found that incorporation of supervised carbimide and the similar medication, disulfiram, into a comprehensive treatment program resulted in an abstinence rate of over 50%.

Ken Ferguson and Gordon Bell, who tested the medication on themselves.

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