Camalexin (3-thiazol-2-yl-indole) is a simple indole alkaloid found in the plant Arabidopsis thaliana and other crucifers.
The secondary metabolite functions as a phytoalexin to deter bacterial and fungal pathogens.
[1] The base structure of camalexin consists of an indole ring derived from tryptophan.
[1] A glutathione conjugate followed by a subsequent unknown enzyme is needed to form dihydrocamalexic acid.
[6][7] Camalexin is cytotoxic against aggressive prostate cancer cell lines in vitro.