The Candigliano is a river in the Marche and Umbria regions of Italy.

The river flows east and forms the border between Pesaro e Urbino and Perugia for a short distance south of Mercatello sul Metauro before entering Pesaro e Urbino.

It then continues flowing east past an exclave called Monte Ruperto belonging to Città di Castello and then past Piobbico, where it is joined by the Biscubio.

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