Most bacterial capsules are composed of polysaccharide,[4] but some species use other materials, such as poly-D-glutamic acid in Bacillus anthracis.
To visualize encapsulated bacteria using a microscope, a sample is treated with a dark stain, such as India ink.
When viewed,JB bacterial capsules appear as a bright halo around the cell on a dark background.
The capsule is considered a virulence factor because it enhances the ability of bacteria to cause disease (e.g. prevents phagocytosis).
[24][25] Capsules too small to be seen with an ordinary microscope, such as the M protein of Streptococcus pyogenes, are called microcapsules.