The turnpike then entered Ashland 48 miles (77 km) from Reading, a half-mile west of which was located toll gate #7, just past the community of Germantown.
It continued in a northwest course over Red Ridge (current route of PA-54) and up the south side of Big Mountain to Natalie at the top.
From Paxinos, the turnpike followed the present Pennsylvania Route 61 until it crossed Shamokin Creek, just east of Sunbury.
In 1822, the rate of tolls (per mile) were: The Centre Turnpike followed the path of the King's Highway, which had been surveyed in 1770 by Francis Yarnall.
[1] A purchaser appeared in 1884, being the Pennsylvania Railroad Company, who desired to extend their Schuylkill Division from Reading to Pottsville and New Boston.
In building this section between Reading and Pottsville they encountered great difficulty on account of the Centre Turnpike being in the way of construction.