Chemical library

In the drug discovery process for instance, a wide range of organic chemicals are needed to test against models of disease in high-throughput screening.

Depending upon their scope and design, chemical libraries can also be classified as diverse oriented, Drug-like, Lead-like, peptide-mimetic, Natural Product-like,[1] Targeted against a specific family of biological targets such Kinases, GPCRs, Proteases, PPI etc.

Chemoproteomics is a field of study that incorporates the use of chemical libraries to identify protein targets.

Additional chemistry work may be needed to further optimize the chemical library in the active portion of the subspace.

When it is needed, more synthesis is completed to extend out the chemical library in that particular subspace by generating more compounds that are very similar to the original hits.

This new selection of compounds within this narrow range are further screened and then taken on to more sophisticated models for further validation in the Drug Discovery Hit to Lead process.

Some chemicals are fairly unstable, radioactive, volatile or flammable and must be stored under careful conditions in accordance with safety standards such as OSHA.