Chlorendic acid is slightly soluble in water and nonpolar organic solvents (e.g. benzene, hexane, carbon tetrachloride).

When reacted with nonhalogenated glycols, it forms halogenated polyols that can be used as flame retardants in polyurethane foams.

Esters and amine salts of chlorendic acid are used as extreme pressure additives in synthetic lubricants.

It may, however, be released when such materials are subjected to hydrolysis, and it can be formed by oxidation of chlorinated cyclodiene insecticides (e.g. endosulfan, chlordane, heptachlor, aldrin, dieldrin, endrin, and isodrin).

In Europe, 80% of chlorendic acid is used in the production of flame-resistant composites for building and transportation, while the rest is used in materials for corrosion-resistant fluid-storage equipment.