It is highly flammable when exposed to temperatures above 200 °C[7] In the presence of oxidizing agents aldrin reacts with concentrated acids and phenols.

Aldrin is synthesized by combining hexachlorocyclopentadiene with norbornadiene in a Diels-Alder reaction to give the adduct.

[10] The estimated production volume of aldrin in the US peaked in the mid-1960s at about 18 million pounds a year and then declined.

Degradation by ultraviolet radiation or microbes can convert dieldrin to photodieldrin and aldrin to photoaldrin.

Studies have shown that aldrin stimulates the central nervous system (CNS), which may cause hyperexcitation and seizures.

The second mechanism makes use of aldrin's ability to block gamma-aminobutyric acid (GABA) activity.

Aldrin induces neurotoxic effects by blocking the GABAA receptor-chloride channel complex.

In addition, the adverse effects after exposure to aldrin are demonstrated, indicating the risk regarding the compound.

The ability of aldrin, in its use for the control of termites, is examined in order to determine the maximum response when applied.

In 1953 US researchers tested aldrin and dieldrin on terrains with rats known to carry chiggers, at a rate of 2.25 pounds per acre (2.52 kg/ha).

The aldrin treatment indicate a high productivity, especially in comparison to other insecticides that were used at the time, such as DDT, sulfur or lindane.

[20] Exposure of aldrin to the environment leads to the localization of the chemical compound in the air, soil, and water.

However the main adverse effect of aldrin and dieldrin is in relationship to the central nervous system.

[22] Besides that other symptoms were also reported like headaches, nausea and vomiting, anorexia, muscle twitching and myoclonic jerking and EEG distortions.

Immunological tests linked an antigenic response to erythrocytes coated with dieldrin in those cases.

[29] Further, an IDLH limit has been set at 25 mg/m3, based on acute toxicity data in humans to which subjects reacted with convulsions within 20 minutes of exposure.

11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.