Capitolina's paternal grandfather, was an Egyptian Greek Grammarian and Astrologer called Thrasyllus of Mendes or Tiberius Claudius Thrasyllus, who was a friend of the Roman Emperor Tiberius, while her paternal grandmother was Greek Princess Aka II of Commagene, who was a great, granddaughter of King Antiochus I Theos of Commagene.
After Epiphanes married Capitolina, they settled and lived in the court of her father-in-law King Antiochus IV of Commagene.
In 72 Lucius Caesennius Paetus, the Roman Governor of Syria had sent letters addressed to Roman Emperor Vespasian accusing Antiochus IV, Epiphanes and Epiphanes’ brother Callinicus in planning to revolt against Rome and allying themselves with the King of Parthia.
The client Kings Aristobulus of Chalcis and Sohaemus of Emesa also supplied troops to Paetus.
Vespasian brought peacefully back to Rome, Epiphanes; Capitolina, their son with Callinicus in an honourable Roman Military Escort.
Capitolina; Epiphanes, their son with Callinicus lived in Rome with Antiochus IV for the remainder of his life.
After the death of Antiochus IV, Capitolina; Epiphanes and their family moved and finally settled in Athens Greece.
These surviving inscriptions are honorific ones, which dedicate and honor Capitolina as the daughter of Balbilus and as an honorary participate of the Balbillean Games at Ephesus.
Capitolina lived her remaining years in Egypt and married the politician Marcus Junius Rufus between 94 and 98.