[1] She lived in her life at the French royal court and performed many successful assignments as a mediator.

She and her sisters lost their mother in 1582 and their father in 1584 and were taken care of by their stepmother Louise de Coligny, with whom they had a very good relationship.

In 1594 Louise introduced the elder sisters Elisabeth and Charlotte Brabantina at the court of Henry IV of France in order to find French Huguenot spouses for them.

Louis XIII appointed her to chair the synod between the French reformed churches in Vitry in May–June 1617.

[2] She maintained a correspondence with her stepmother and her sisters, who were also often politically active, and they often referred to themselves as 'femmes d'état' or female "statesmen".