The hospital's census declined by the early 1960s, and unused portions were sold off and developed into the Queens County Farm Museum, a school campus, and a children's psychiatric center.

The local railroad station - on a line running from Long Island City to Bethpage - took the name "Creedmoor;" apparently coined by British visitors in reference to the local geography and former use of the site as a rifle range having been reminiscent of the moors back in Britain, owing to the designation "Creed's Moor.

[3] In 1892, as a result of declining public interest and mounting noise complaints from the growing neighborhood, the NRA deeded its land back to the state.

Intakes at the former National Guard barracks rapidly expanded over the coming years, with a self-reported census reported a total of 150 inpatients housed at Creedmore by 1918.

In December 1977, one of Creedmoor's most notorious patients, former NYPD officer Robert Torsney, was committed to the hospital after being found not guilty by reason of insanity for the 1976 murder of then-15 year-old Randolph Evans in Brooklyn.

[7] In August 2023, a shelter for migrants opened at Creedmoor Psychiatric Center, amid a sharp increase in the number of asylum seekers traveling to the city.