The large property is bound by Parsons Boulevard to the west and 164th Street to the east, with Goethals Avenue to the north.

[3][7][8][9] The main building, opened in 2001, is located at the southwest corner of 164th Street and 82nd Road just north of the Grand Central Parkway.

[3][10] The building was designed by the Perkins and Will and Davis Brody Bond architectural firms, with a largely-glass outer facade.

[3][10][1] It features private and semi-private patient rooms, in contrast to the large hospital wards of the previous buildings.

[17][16][18] The outer facade consists of precast concrete, with glass curtain walls on the east (front) and south faces.

[17][16][19] Services provided at The Pavilion include a diabetes treatment center, primary care, child development and early childhood intervention, pediatrics, psychiatry, ophthalmology, and dentistry.

[33][34][35] The two-story Art Deco brick building was completed in 1932, built along with the original Queens General Hospital, and was considered a modern facility at the time of its construction.

The EMS station, designed by Dean-Wolf Architects, has a glass and aluminum outer facade, a steel frame, and a concrete foundation with a cantilever shape due to the topography of the area.

[36][49] The original main Queens General Hospital building fronted 164th Street between 82nd Road and the power plant, on the site of the current Pavilion.

[36][37][45] Along Goethals Avenue, where the Queens Gateway School and EMS station now sit, were (from east to west) the power plant, a laundry facility, a garage for ambulance storage, an industrial workshop for creating furniture and other items, and the mortuary building.

[33] The Q65 bus route runs north-to-south along 164th Street on the east side of the campus, serving the main buildings.

[2] A significant portion of the service area consists of South Asian immigrants from nations such as India, Pakistan, and Bangladesh, as well as Guyanese.

[77] The primitive dirt roads surrounding the hospital including 164th Street were improved and paved, with Works Progress Administration funds.

[83][84][85][86] On October 30, 1935, the hospital was dedicated, with Mayor Fiorello H. La Guardia, commissioner Goldwater and Queens Borough President George U. Harvey in attendance.

[45] Among the then-modern medical innovations at the hospital were specialized X-ray equipment, radium for the treatment of cancer (a practice now obsolete), and an iron lung.

[3][95] In spite of the unification, Queens General and Triboro Hospital continued to operate largely independent of each other.

[98][99] Beginning in fall 1954, Queens Hospital Center and Queens College began an experimental two-year nursing program free of tuition, funded by a $50,000 grant from the Board of Higher Education of the City of New York (now the City University of New York).

[104] At this time there were plans to construct an expansion of the medical center in between the Triboro and Queens General buildings, adding up to 1,000 beds.

[105][107] The primary location of interest was a site on Liberty Avenue adjacent to the west of the future York College campus between Jamaica and South Jamaica, just south of the Long Island Rail Road Main Line and abutting its Atlantic Branch.

[114][113] Other plans included building on an alternate South Jamaica site, and rebuilding the hospital on its current property.

[115] Local residents and members of Queens Community Board 8 (representing Hillcrest) were in fact opposed to the relocation of the hospital.

In particular, the city and Mayor David Dinkins were searching for a deal with a "minority" medical school, which would have a majority Black and/or Latino student population that would reflect the hospital's patient demographics.

[117] In 1993, Mount Sinai assumed control of Queens Hospital's OB-GYN program, replacing LIJ.

[119] A 1992 survey by the Joint Commission on Accreditation of Healthcare Organizations cited Queens Hospital Center for several safety violations, including "dead-end corridors, inadequate egress, poor ventilation and shared toilet facilities.

[48][46][123] The plans to sell the hospital also prevented Queens Gateway Secondary School from being moved onto the campus.

[124] In March 1995, the pastor of the Ebenezer Baptist Church in Flushing went on a hunger strike in protest of the proposed sales of the hospitals.

[46] On August 19, 1997, after the failed sale, Mayor Giuliani announced plans to construct state-of-the-art buildings on the Queens Hospital Center campus.

[134] The project was financed with taxable municipal bonds issued from the Dormitory Authority of the State of New York, in order to lower costs in the event the city decided to sell the hospital in the future.

[46] The new Queens Hospital Center, which cost $147 million to construct,[133] was opened December 5, 2001, at a ribbon-cutting ceremony attended by Mayor Giuliani.

[15] Queens Gateway to Health Sciences Secondary School opened at the north end of the campus in fall 2010.