Keene grew up in Littleton, Colorado and attended Chatfield High School, where he played middle linebacker and running back on the football team and also ran track.
[2] Keene started 12 games as a true freshman and caught 10 passes for 167 yards.
[3] He was named honorable mention All-Atlantic Coast Conference after recording 28 receptions for 341 yards and three touchdowns in his sophomore season.
[6] Following the end of the season, Keene announced that he would forgo his final year of eligibility to enter the 2020 NFL Draft.
[7] Keene finished his collegiate career with 59 receptions for 748 yards and eight touchdowns in 39 games played.
[8] Keene was selected in the third round with the 101st overall pick in the 2020 NFL draft by the New England Patriots.