[9] Smith made his NFL debut in Week 1 against the Atlanta Falcons but did not record any meaningful statistics.

[11] He recorded a season-high and team-leading 60 receiving yards on three receptions against the Oakland Raiders in the following game.

[15] In Week 16 against the New Orleans Saints on Christmas Day, Smith had two receiving touchdowns during the 52–33 loss.

[17] On September 1, 2021, it was revealed that Smith underwent surgery to repair a torn meniscus, which prevented him from playing for the entire 2021 season.

[19] On November 1, 2022, Smith was placed on injured reserve after suffering an ankle injury in the Week 8 win over the Arizona Cardinals.

During the Vikings' Wild Card Round loss to the New York Giants, Smith had a receiving touchdown.

[24] Smith suffered a hamstring injury during the Bengals' Week 3 win against the Los Angeles Rams.