After finishing his PhD, he completed a postdoc at the Delft University of Technology (2007), doing research in nanoelectrode fabrication and single molecule experiments using nanopores under the supervision of Cees Dekker and Serge Lemay.
[1] Since 2007, Krapf is a faculty member in Colorado State University, where he currently heads a Biophysics lab that focuses on anomalous diffusion and cellular architecture using a combination of analytical and experimental tools including single particle tracking and super-resolution imaging.
[2][3] In 2011, Krapf and his team at Colorado State University showed that the motion of membrane proteins on the surface of mammalian cells display anomalous diffusion with a non-ergodic underlying physical mechanism.
[5][6] In 2017, the Krapf lab discovered that due to complex branching processes the actin cytoskeleton adjacent to the plasma membrane of mammalian cells form an intricate fractal structure.
In 2018, an international team led by Krapf involving researchers from the University of Massachusetts and the Instituto de Biología y Medicina Experimental (Argentina) revealed the organization of the actin-based cytoskeleton in the sperm flagellum using three-dimensional super-resolution imaging.