[citation needed] It catalyzes the reduction of uracil and thymine.

[4] It also participates in beta-alanine metabolism and pantothenate and coa biosynthesis.

Other names in common use include: As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1GT8, 1GTE, 1GTH, 1H7W, and 1H7X.

Genetic deficiency of this enzyme results in an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

[2] Click on genes, proteins and metabolites below to link to respective articles.