Dipeptide

Because dipeptides are prone to hydrolysis, the high solubility is exploited in infusions, i.e. to provide nutrition.

The two modified amino acids are then combined in the presence of a coupling agent, which facilitates formation of the amide bond: Subsequent to this coupling reaction, the amine protecting group P and the ester are converted to the free amine and carboxylic acid, respectively.

[1] Dipeptides are produced from polypeptides by the action of the hydrolase enzyme dipeptidyl peptidase.

[5] Dietary proteins are digested to dipeptides and amino acids, and the dipeptides are absorbed more rapidly than the amino acids, because their uptake involves a separate mechanism.

Dipeptides activate G-cells found in the stomach to secrete gastrin.

Glycylglycine is the simplest dipeptide.
Aspartame is produced commercially as an artificial sweetener.
Retosiban [ 6 ] is a cyclic dipeptide being investigated as an oral drug .