This district is in New York State's southern tier and encompasses an area of 110 square miles (280 km2) and serves a population of about 1900 students.

Few Advanced Placement courses are offered each year and are contingent on school funding and teacher availability.

Dryden High School also has programs set up with TST Boces where juniors and seniors can pursue vocational studies, including welding, culinary arts, and cosmetology, among others.

In 2018, the high school put on a production of Legally Blonde, and were recognized by the Cortland Repertory Theater Pavilion Awards.

[31] Dryden High School is often recognized in the regional Scholastic Art Awards.

The Dryden Central School district is predominately white, with the population of the school district being 86% white, 6% multiracial, 4% Hispanic or Latino, 2% Black or African American, and 1% Asian or Pacific Islander, as of 2019.

The combined buildings house many classrooms as well as two gymnasiums, a pool, two cafeterias, multiple computer laboratories, an auditorium and the school library.

Two propositions passed: the first approved the installation of a synthetic turf field on Dryden's Volante Field, along with better drainage systems and sound systems, and the second approved the district's acquisition of property at 22 Pleasant Street.

In addition, the school uses the Websense program which filters out potentially offensive/disruptive websites on the internet.