Laboratory signs of FHH include:[citation needed] Types include: Most cases of FHH are associated with loss of function mutations in the calcium-sensing receptor (CaSR) gene,[3] expressed in parathyroid and kidney tissue.
As a result, inhibition of parathyroid hormone release does not occur until higher serum calcium levels are attained, creating a new equilibrium.
Commonly, the parathyroid hormone level is checked and may be slightly elevated or also on the high normal end.
If urine calcium is not checked, this may lead to parathyroidectomy for presumed primary hyperparathyroidism Additionally as the name implies, there may be a family history of benign hypercalcemia.
No treatment is generally required, as bone demineralisation and kidney stones are relatively uncommon in the condition.