James Colbert George Rogers Clark 120 soldiers unknown, but significant Fort Jefferson was a town on the Mississippi River, about one mile south of Wickliffe, Kentucky in southwestern Ballard County.
Henry would also propose this idea to George Rogers Clark, who saw it as a fortification for frontier protection and conquest of British Indian allies.
Clark would later press Henry's successor, Thomas Jefferson, on the importance of a fort along both rivers, to control commerce and stop British supplies.
Jefferson would also write to Joseph Martin that "the ground at the mouth of the Ohio on the south side belonging to the Cherokee, we would not meddle in without their leave".
In 1782, four Chickasaw chiefs sent a letter to American military post commanders in the West to initiate peace negotiations, stating, "What damage occurred because you established a fort in our hunting grounds without our permission, and at that location, you suffered most from us."