The Planet Express crew enter Fry's dreams and find themselves back in the year 1999 in search of a mysterious alien song.
The title is a spoof of Game of Thrones, while the episode as a whole makes many references to Close Encounters of the Third Kind and Inception, and the plot contains many similarities to Star Trek IV: The Voyage Home.
Earth is slowly approached by a mysterious alien ship that repeatedly broadcasts four loud musical tones, which can be heard by everyone on the planet.
At first, the music is merely an annoyance, but as the ship draws nearer, the booming tones begin to cause structural damage and threaten to tear the planet apart.
Accompanying Nibbler, Digby used a key fob, coincidentally at the very instant that Fry fell in, to remotely lock the spaceship.
Heading home, having forgotten where they had parked their ship, a drunken Digby dropped the fob, with keys attached, down a storm drain.
Forced to take a cab back to their base on Vergon 6, Digby had later retrieved a spare set of keys, and has been traveling from one planet to another, broadcasting the security signal in an attempt to locate the "company car".
Fry leads them to the roof of the Applied Cryogenics building, where the Nibblonian ship still rests, ransacked, with a dead battery.
[1] Max Nicholson of IGN gave the episode a 7.3/10 "Good" rating, saying "Futurama's "Game of Tones" included a fun trip to Fry's past, though it lacked the emotional weight of previous visits.