It borders Georgia to the north and Armenia to the south and west, and the Ganja-Dashkasan Economic Region to the east.

The region consists of the districts of Aghstafa, Gadabay, Gazakh, Shamkir, and Tovuz.

[3] It has an area of 7,030 square kilometres (2,710 sq mi).

Its population was estimated to be at 687.6 thousand people in January 2021.

Its territory was part of the larger Ganja-Qazakh Economic Region prior to 2021.