During the Axis occupation of Greece (1941–44), Athens was controlled by German military fourses, and the line used for the transport of troops and weapons.

On 25 November 1942, 150 Greek partisans, following plans drawn by E. C. W. "Eddie" Myers and assisted by a group of British SOE officers, blew up the railroad bridge over the Gorgopotamos river, cutting off the enemy-controlled route between Thessaloniki and Athens.

The track and rolling stock replacement took time following the civil war, with normal service levels resumed around 1948.

On 1 January 1971 the station, and most of the Greek rail infrastructure were transferred to the Hellenic Railways Organisation S.A., a state-owned corporation.

Freight traffic declined sharply when the state-imposed monopoly of OSE for the transport of agricultural products and fertilisers ended in the early 1990s.

[11] On 10 February 2018, The historical Gorgopotamos Bridge stopped serving trains, putting an end to over a century of service; now, railway passengers from Athens heading north to Thessaloniki will not pass through the scenic Gorgopotamos bridge that connects Bralos mountain with Lamia.