[9][10] In the peace agreements of the 30 Years' War (1648) the Duchy of Luxembourg lost lands to the Kingdom of France during the reign of the French King Louis XIV.

[13] During much of the 19th century Greece and the Grand Duchy of Luxembourg were trying to gain their independence from the foreign powers which had controlled them in the previous 300 years.

The Greek War of Independence (1821-1828) against Ottoman rule was started by General Alexandros Ypsilantis's unsuccessful revolt in Moldavia (modern-day Romania) during the spring of 1821.

[8][14] Despite the revolt failing to achieve Moldavian autonomous rule, it led to widespread unrest in Greece, especially Morea (the Peloponnese).

[9][10][13] Under the rule of King William II of the Netherlands reforms were gradually enacted as he was in favor of Luxembourg's independence.

Luxembourg’s embassy in Greece was originally located on Skoufa Street before being moved to Vasilissis Sofia Avenue in 2003.

Greece’s largest exports to Luxembourg are petroleum gas (81.8%), electricity (6.64%), rolled tobacco (2.06%), and insulated wire (1.42%).

Luxembourg’s largest exports to Greece are petroleum gas (33.2%), electricity (11.3%), plastic products (5.72%), and raw aluminum (5.36%).