Hathoway Slough is a 6.39 mi (10.28 km) long second-order tributary to Big Springs Creek (South Branch Verdigre Creek tributary) in Antelope County, Nebraska.

Hathoway Slough rises on the Elkhorn River divide about 1 mile east of Orchard, Nebraska in Antelope County and then flows northeast and northwest to join Big Springs Creek about six miles [CONVERT]north-northeast of Orchard, Nebraska.

[1] Hathoway Slough drains 7.54 square miles (19.5 km2) of area, receives about 26.3 in/year of precipitation, has a wetness index of 555.68, and is about 2.24% forested.

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