Hexacene is an aromatic compound consisting of six linearly-fused benzene rings.

It is a blue-green, air-stable solid with low solubility.

It and other acenes and their derivatives have been investigated in potential applications related to organic semiconductors.

Like larger acenes, hexacene is poorly soluble, but derivatives have been prepared with improved solubility, such as 6,15-Bis(tri-t-butylsilylethynyl)hexacene, which melts with decomposition at 96 °C.

One route uses thermal decarbonylation of a monoketone precursor.